Skip to content

Anti-aging / hydrating peptide

ACETYL HEXAPEPTIDE-37

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic hexapeptide marketed as Diffuporine, used to boost aquaporin-3 driven hydration and stimulate collagen production. Peptide class has a clean cosmetic safety profile, with supplier studies showing smoother and firmer skin.

Function

SKIN CONDITIONING

Skin benefits

  • Boosts aquaporin-3 expression and skin hydration
  • Stimulates collagen I synthesis in fibroblasts
  • Improves smoothness, firmness and barrier function

Known concerns

  • Cost may push formulators to under-dose below efficacious levels
  • Stability sensitive to formulation pH and storage
  • Limited long-term independent data outside supplier studies

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Check your shelf

Find ACETYL HEXAPEPTIDE-37 in your products.

Scan any cosmetic product with LuxSense to see if it contains ACETYL HEXAPEPTIDE-37 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.