Antimicrobial
ACETYL ISOLEUCYL D-OLIGOPEPTIDE-1 AMIDE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 15-amino-acid synthetic peptide with broad-spectrum antimicrobial activity, modeled on a sequence from the eastern brown snake; used as a preservative.
A synthetic D/L hybrid oligopeptide of 15 amino acids with the C-terminus modified to an amide, derived from a 12-amino-acid Vipericidin sequence found in the eastern brown snake. The D-amino acid configuration increases protease resistance. PubChem safety score: 80. Not restricted under EU Annex II or III; the synthetic peptide design and D-amino acid incorporation reduce allergenic potential compared to natural peptide counterparts.
Function
Skin benefits
- Antimicrobial
- Anti-sebum
- Preservative
- Skin conditioning
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related antimicrobials
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.