Skin Conditioning
ACETYL OCTAPEPTIDE-57
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
An acetylated eight-amino-acid peptide, sold for expression-line smoothing. Standard peptide safety profile; efficacy is supplier-claimed.
Acetyl octapeptide-57 is a synthetic octapeptide with an N-terminal acetyl group, positioning it in the "Argireline-like" family of peptides marketed for softening expression lines and relaxed-skin appearance. The acetyl cap often improves molecular stability versus free amine peptides. Used at low ppm levels in serums. No SCCS or CIR review for this specific peptide identified; supplier-commissioned studies form the basis of efficacy claims. No GHS hazards at cosmetic concentrations.
Function
Skin benefits
- N-acetylated octapeptide for skin conditioning and expression-line reduction claims
- Acetylation may improve stability in formulation
- Used at low parts-per-million concentrations
Known concerns
- Proprietary ingredient with supplier-led evidence
- Anti-wrinkle efficacy claims exceed independent data
- No dedicated regulatory dossier
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.