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ACETYL ORNITHINE

85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An amino acid derivative naturally found in skin that signals cells to produce more collagen and elastin — a firming ingredient that helps restore skin's youthful bounce.

Acetyl ornithine (N-acetyl-L-ornithine) is a modified amino acid and derivative of arginine. It is naturally present in the urea cycle and acts as a precursor to proline, which is critical for collagen synthesis. Studies suggest acetyl ornithine can stimulate fibroblast activity and increase collagen production. It also acts as a humectant. The acetylated form improves skin penetration compared to basic ornithine. Safe at cosmetic concentrations with no irritation or sensitization profile.

Function

SKIN CONDITIONING

Skin benefits

  • Stimulates collagen synthesis
  • Firms and tones skin
  • Supports cellular energy metabolism
  • Humectant hydration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.