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Conditioning Agent

ACETYL SH-HEXAPEPTIDE-5 AMIDE ACETATE

84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A lab-made peptide used for skin-conditioning claims and smoother-looking skin.

Acetyl sh-Hexapeptide-5 Amide Acetate is the acetate salt of the product obtained by the acetylation of sh-Hexapeptide-5 SP in which the C-terminus of the peptide is an amide. This is a synthetic or recombinant peptide used for skin-conditioning claims and is typically present at low concentrations. The main limitation is that safety and efficacy evidence is usually ingredient-specific and much thinner than for classic moisturizers.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning

Known concerns

  • Limited ingredient-specific clinical data
  • Possible irritation in highly reactive skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related conditioning agents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.