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ACETYL SH-HEXAPEPTIDE-8 SP

84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An acetylated hexapeptide commonly used in anti-wrinkle and expression-line cosmetic formulations for its botox-like targeting properties.

Acetyl sh-Hexapeptide-8 SP is a synthetic hexapeptide with acetyl modification, similar to other peptide-based anti-aging ingredients used in cosmetics. Not restricted under EU Cosmetics Regulation 1223/2009. The ingredient has been studied for its ability to reduce the appearance of expression lines and has shown good tolerability in topical applications.

Skin benefits

  • May reduce appearance of expression lines
  • Supports skin smoothness and youthful appearance

Known concerns

  • Generally very well tolerated; minimal sensitization risk

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.