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ACETYL SH-PENTAPEPTIDE-1

86

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic signal peptide that mimics the N-terminal end of elastin, used in anti-aging skincare to help boost collagen production and improve skin elasticity.

Acetyl sh-Pentapeptide-1 is a short-chain synthetic peptide that functions as a collagen-stimulating signal molecule. It is not subject to EU Annex restrictions and is considered safe for cosmetic use at normal concentrations, though comprehensive long-term human safety data remain limited due to its relatively recent adoption in formulations.

Skin benefits

  • Stimulates collagen synthesis
  • Improves skin elasticity and firmness
  • Reduces appearance of fine lines

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.