Skin Conditioning
ACETYL TETRAPEPTIDE-71
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An N-acetylated tetrapeptide marketed for soothing and barrier support. Typical short-peptide profile, but evidence is supplier-led.
Acetyl tetrapeptide-71 is a four-amino-acid sequence with an acetyl group on its N-terminus, a common modification that improves stability and skin penetration versus free peptides. It is supplied at very low active percentages and positioned for soothing, elasticity, or barrier support depending on the specific sequence. The class of acetylated short peptides has a long track record of low irritation in cosmetic use, though this exact grade has no independent CIR or SCCS assessment, and published efficacy data is minimal. Best treated as a gentle functional ingredient rather than a clinically validated active.
Function
Skin benefits
- Soothing and barrier-support signaling
- Gentle, low-irritation profile
Known concerns
- No independent safety monograph
- Supplier-sourced efficacy claims
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.