Acetylcholine perchlorate
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
The perchlorate salt of acetylcholine, a neurotransmitter. This is a pharmaceutical agent, not a cosmetic ingredient, and raises significant safety concerns due to the perchlorate anion.
Acetylcholine Perchlorate is the perchlorate salt of acetylcholine, the primary neurotransmitter at neuromuscular junctions and in the parasympathetic nervous system. Perchlorate is a known contaminant that interferes with iodide uptake in the thyroid (perchlorate is a competitive inhibitor of the sodium-iodide symporter). The combination of a potent pharmacological agent with a thyroid-disrupting anion makes this compound highly unsuitable for cosmetic use. No data support its safety in topical applications.
Skin benefits
- No cosmetic skin benefits established
Known concerns
- Perchlorate anion: thyroid hormone synthesis disruption
- Potent pharmacological agent — not appropriate for cosmetics
- Neuromuscular activity risk
- No safety assessment for topical use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.