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active

adrenalone

CAS 99-45-6
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Adrenalone is a sympathomimetic vasoconstrictor used in pharmaceuticals, not cosmetics. Systemic cardiovascular effects and its drug classification make it inappropriate for general cosmetic use in the EU.

Skin benefits

  • Historically used as a topical vasoconstrictor in pharmaceutical preparations
  • Can reduce visible redness via vascular effect

Known concerns

  • Classified as a pharmaceutical active, not a cosmetic ingredient in the EU
  • Systemic vasoconstrictor effects exceed cosmetic scope
  • Risk of cardiovascular side effects if absorbed
  • Not approved for general cosmetic use
  • Sympathomimetic activity inappropriate for leave-on cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.