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ALOE ARBORESCENS LEAF PROTOPLASTS

CAS 223747-76-0
86

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Protoplasts (cell wall-free plant cells) derived from Aloe arborescens leaves, used as a highly bioavailable form of aloe in advanced skincare.

Aloe arborescens protoplasts are cells that have had their cell walls removed, making their contents directly bioavailable. Aloe arborescens is used in traditional wound healing and is chemically similar to A. barbadensis. EU Regulation 1223/2009 does not restrict Aloe arborescens-derived ingredients. The protoplast form may pose slightly higher allergenic potential due to direct cytoplasmic exposure, warranting patch testing in sensitive individuals. CAS 223747-76-0.

Skin benefits

  • Higher bioavailability of aloe bioactives due to absent cell wall
  • Retains antioxidant and wound-healing properties of Aloe arborescens

Known concerns

  • Protoplast form may increase exposure to intracellular compounds including anthraquinones
  • Sensitization potential slightly elevated vs. whole plant extracts

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.