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AMIDINOGLYCINE

CAS -
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An amino acid derivative sometimes used in anti-aging formulations, though its safety profile requires careful formulation to avoid irritation.

Amidino Glycine (guanidinoacetic acid or closely related structure) contains a guanidine group attached to a glycine backbone. While glycine itself is very safe, guanidine derivatives can be reactive and potentially irritating at higher concentrations. The CAS number listed as '-' is non-standard, suggesting ambiguity. Not specifically listed on EU Annex II or III, but requires standard safety assessment. Anti-glycation and advanced glycation end-product (AGE) inhibition are cited mechanisms in skin care contexts.

Skin benefits

  • anti-glycation activity
  • moisture binding
  • potential anti-aging benefits

Known concerns

  • potential skin irritation at high concentration
  • ambiguous CAS identifier
  • limited toxicological data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.