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AMINOPROPYL TRIMETHOXYSILANE

CAS 13822-56-5
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A reactive aminosilane with severe corrosion and irritation warnings that is restricted in EU Annex III for cosmetic use.

Aminopropyl trimethoxysilane is a reactive organosilane with primary amine functionality. It carries severe GHS hazard classifications including skin corrosion (H314), skin irritation (H315), serious eye damage (H318), and eye irritation (H319). The ingredient appears in EU Annex III with restrictions for its use in cosmetic products. The reactive methoxysilane groups can cause sensitization. Concentration limits and specific product type restrictions apply.

Skin benefits

  • Surface modification agent

Known concerns

  • EU Annex III restricted
  • Corrosive (H314)
  • Serious eye damage (H318)
  • Skin irritation (H315, H319)
  • Reactive silane can cause sensitization

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.