AMMONIUM NONOXYNOL-4 SULFATE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An anionic surfactant derived from nonoxynol with moderate skin compatibility concerns due to its ethoxylation chain length and potential irritation.
Ammonium nonoxynol-4 sulfate is the ammonium salt of a sulfated ethoxylated alkyl ether, specifically the sulfate of Nonoxynol-4. It is listed in EU CosIng without specific restriction at current use levels. However, nonoxynol compounds with low degrees of ethoxylation (like 4) have raised concerns due to potential for irritation and the presence of residual monomers. The surfactant activity is moderate, and it is primarily used in rinse-off formulations. PubChem safety score of 48 aligns with moderate concern for low-EO nonionic surfactants.
Skin benefits
- Effective cleansing and foaming for rinse-off products
Known concerns
- Low ethoxylation degree raises irritation concerns
- Potential residual monomer content
- More suitable for rinse-off formulations
- May affect aquatic environment at high concentrations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.