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Hair Care Active

AMMONIUM THIOGLYCOLATE

CAS 5421-46-5 Updated
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ammonium thioglycolate breaks hair disulfide bonds in perms and depilatories. PubChem flags acute oral toxicity, skin sensitization, and eye irritation. EU restricts use to professional levels.

Function

DEPILATORYHAIR WAVING OR STRAIGHTENINGREDUCING

Skin benefits

  • Permanent wave restructuring
  • Chemical depilation

Known concerns

  • Acute oral toxicity
  • Skin sensitizer (well-documented thioglycolate allergy)
  • Serious eye irritant
  • Corrosive
  • EU Annex III restricted

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.