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AMYL ISOBUTYRATE

CAS 2445-72-9
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An ester of amyl alcohol and isobutyric acid — primarily used as a fragrance ingredient that imparts a fruity, pear-like scent to cosmetics.

Amyl Isobutyrate (also called isoamyl isobutyrate or 3-methylbutyl isobutyrate) is a fatty acid ester with a characteristic fruity-woody odor. It is listed as a fragrance allergen in EU Annex III (regulated for fragrance sensitization) due to its presence in essential oils that require declaration above 0.001% in leave-on products. While the compound itself shows low acute toxicity, its classification as a fragrance allergen triggers mandatory labeling requirements in the EU.

Skin benefits

  • Provides pleasant scent experience, which can be psychologically beneficial

Known concerns

  • EU-regulated fragrance allergen — must be declared on product label
  • May cause contact dermatitis in sensitized individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.