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AMYLCINNAMAL/METHYL ANTHRANILATE SCHIFF BASE

CAS 68527-78-6
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A Schiff base fragrance containing amylcinnamal moieties; amylcinnamal is a known fragrance allergen requiring declaration in the EU.

Amylcinnamal (also called amyl cinnamal) is listed in EU Regulation 1223/2009 Annex III as a fragrance allergen requiring mandatory declaration when present above 0.001% in leave-on products or 0.01% in rinse-off products. While this specific Schiff base is not directly restricted, it can release amylcinnamal on hydrolysis, making compliance with EU allergen declaration requirements necessary. The existing PubChem score of 60 aligns with fragrance allergen concerns.

Skin benefits

  • Provides distinctive floral-fragrant character to cosmetic products

Known concerns

  • Contains amylcinnamal moieties - a regulated fragrance allergen in the EU
  • Potential for hydrolysis releasing the allergen in aqueous formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.