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AMYLCYCLOPENTENONE

CAS 25564-22-1
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Amylcyclopentenone (CAS 25564-22-1) is a cyclic unsaturated ketone. No CosIng functions listed and no GHS hazard classifications reported. The α,β-unsaturated ketone structure is notable as such compounds can potentially act as Michael acceptors and may have mild sensitization potential. However, at trace fragrance concentrations, the risk is expected to be low. Limited specific toxicological data available. Exercise caution due to limited available safety data.

Amylcyclopentenone is listed in EU Regulation 1223/2009 Annex III under reference 153, indicating a designated fragrance or flavoring restricted substance. The IFRA (International Fragrance Association) has guidelines restricting cyclopentenone derivatives in consumer products due to sensitization concerns at certain use levels.

Skin benefits

  • Used as a fragrance to provide fruity, ketonic notes reminiscent of strawberry or pineapple

Known concerns

  • EU Annex III/153 restricted fragrance material
  • IFRA restrictions apply to cyclopentenone derivatives
  • Limited publicly available safety assessment

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.