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AMYLISOEUGENOL

CAS 10484-36-3
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phenylpropene fragrance similar to eugenol and isoeugenol, carrying fragrance allergen concerns that place it among the EU's designated fragrance sensitizers requiring label declaration.

Amylisoeugenol is a phenylpropanoid ether structurally related to eugenol and isoeugenol, both well-documented fragrance allergens. Like its analogs, it carries a structural alert for sensitization due to the allyl side chain on the aromatic ring. It is not specifically listed in EU Annex III for isoeugenol but the structural similarity suggests it should be treated with equivalent caution.

Skin benefits

  • Used as a fragrance material providing warm, spicy notes

Known concerns

  • Structural alert for fragrance sensitization similar to eugenol/isoeugenol
  • EU IFRA restricts structurally related isoeugenol derivatives
  • Potential cross-reactivity with other phenylpropanoid allergens

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.