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ANDROSTENEDIONYL PROPIONATE

28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A steroid hormone derivative (DHEA analogue) with endocrine activity concerns and EU Annex II/37 restrictions limiting cosmetic use.

Androstenedionyl Propionate is a steroid ester derivative of androstenedione with potential hormonal (androgenic) activity. EU CosIng lists restriction II/37, indicating it falls under regulatory scrutiny for cosmetic use. The androstenedione scaffold raises concerns for endocrine disruption, and the propionate ester may enhance skin penetration, compounding the risk profile.

Known concerns

  • EU Annex II/37 — restricted in cosmetics
  • Potential hormonal/androgenic activity
  • Endocrine disruption concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.