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Anti-androgens of steroidal structure

10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A class of steroid hormone antagonists prohibited in EU cosmetic products at concentrations of 0.1% or higher due to endocrine-disrupting concerns characteristic of hormonal antiandrogens.

Anti-androgens of steroidal structure are hormone antagonists that block androgen receptors or inhibit androgen production. Like other hormonally active substances, they are subject to strict EU regulation. The prohibition in EU Annex II at concentrations >=0.1% reflects the significant endocrine-disrupting potential of these compounds. Hormonal antiandrogens can have profound systemic effects with even low-level exposure.

Known concerns

  • EU Annex II banned at >=0.1%
  • Endocrine-disrupting potential
  • Antiandrogenic hormonal activity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.