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Anti-smallpox globulin

CAS -
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A biological preparation derived from human blood plasma, historically used as a smallpox therapeutic. It has no established role or benefit in cosmetic skincare.

Anti-smallpox Globulin is a human blood-derived immunoglobulin preparation containing antibodies against the smallpox (variola) virus. It was developed as a post-exposure prophylactic or therapeutic for smallpox. It is a biological material of human origin, requiring careful screening for blood-borne pathogens. In cosmetic formulations, its use is highly unusual and safety data for topical application are essentially nonexistent.

Skin benefits

  • No established skin benefits in cosmetic context

Known concerns

  • Risk of blood-borne pathogen transmission (viruses, prions)
  • Potential immunogenic reactions
  • No safety data for topical cosmetic use
  • Biologic of human origin — significant regulatory concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.