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Azacyclonol (INN) and its salts

CAS 115-46-8
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A pharmaceutical psychotropic agent with antihistamine properties, not approved for cosmetic use in the EU.

Azacyclonol is a piperidine derivative that acts as an antihistamine and has been investigated for its psychotropic effects. It carries multiple EU CLP hazard classifications: H302 (acute toxicity), H315 (skin irritation), H319 (eye irritation). It is not listed in EU CosIng and is prohibited in cosmetic products under Regulation 1223/2009 due to its pharmacological activity.

Known concerns

  • Not approved for cosmetic use in EU
  • Acute oral toxicity (H302)
  • Skin and eye irritation (H315, H319)
  • Pharmaceutical activity incompatible with cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.