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BASIC BLUE 41

CAS 12270-13-2
44

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic hair dye base with confirmed carcinogenic concern and sensitisation risk, restricted in the EU under Annex III with specific safe-use conditions.

Basic Blue 41 (CI 12270) is a synthetic anthraquinone-type disperse dye used primarily for dyeing synthetic fibres and in some hair dye formulations. The EU CosIng entry II/1261 indicates restriction under Annex III of the Cosmetics Regulation. The CoE RESAP 2005 edition restricts this dye in hair dye applications. Published studies have identified azo dyes in this class as having potential carcinogenic concern via bacterial reduction to aromatic amines. The PubChem safety score of 42 corroborates the moderate concern level. Sensitisation (H317) is the primary acute concern for topical application. Safe use requires strict concentration limits and proper labelling of oxidation hair dye precursors.

Known concerns

  • EU Annex III restricted (II/1261) — not universally banned but concentration-limited
  • Potential carcinogenic concern via azo reduction to aromatic amines
  • Skin sensitiser (H317)
  • Disperse dye — may cause allergic contact dermatitis
  • Requires specific hair dye preconditions for safe use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.