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Benzilonium bromide (INN)

CAS 1050-48-2
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An anticholinergic quaternary ammonium compound with very limited safety data and pharmacological activity that precludes its use in cosmetic formulations.

Benzilonium bromide is a synthetic anticholinergic quaternary ammonium compound. It has an extremely low PubChem safety score of 3, reflecting its pharmacological nature and toxicity profile. Quaternary ammonium compounds with anticholinergic activity are considered unsuitable for cosmetic use due to their potential systemic effects. The substance is subject to EU Annex III restrictions at concentrations >=0.1%.

Known concerns

  • Very low safety score (3/100)
  • Anticholinergic pharmacological activity
  • Limited safety data for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.