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BENZOYL ISOPROPANOL

CAS 7473-98-5
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A aromatic ketone used primarily in nail and coating applications, known to cause allergic contact dermatitis and phototoxic reactions in some individuals.

Benzoyl isopropanol (also called hydroxyacetophenone or 1-(4-hydroxyphenyl)-2-propanol, though the CAS 7473-98-5 more precisely corresponds to 2-methyl-1-phenyl-2-propanol, a different isomer) is used in nail products and some skincare applications for its fragrance and potential antimicrobial properties. The PubChem safety score of 58 aligns with its classification as a skin sensitiser. EU regulations require declaration of this ingredient if present as a fragrance allergen, and it has been associated with cases of allergic contact dermatitis in nail cosmetic users.

Skin benefits

  • Used as a fragrance ingredient in cosmetic formulations
  • May function as an antioxidant in some formulations

Known concerns

  • Known skin sensitiser - risk of allergic contact dermatitis
  • Associated with nail product dermatitis (photocontact allergy)
  • Requires fragrance allergen declaration in EU if applicable
  • Not specifically assessed by SCCS for cosmetic safety

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.