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BETA-HYDROXYPHENETHYL ACETATE

CAS 10522-41-5
62

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An aromatic alcohol acetate with a free hydroxyl group that may act as a skin sensitizer through metabolic activation.

Beta-hydroxyphenethyl acetate contains a phenolic hydroxyl group which can undergo oxidation to reactive quinone methide intermediates, a known sensitization pathway. No EU harmonised classification exists, but the structural alert warrants caution in leave-on formulations for sensitive skin. The cosmetic use history is limited compared to closely related compounds like phenethyl acetate.

Skin benefits

  • Fragrance material with sweet, floral, rose-like character

Known concerns

  • Structural alert for skin sensitization (quinone methide formation)
  • Limited cosmetic use history

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.