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BETULIN

CAS 473-98-3
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A naturally occurring triterpene from birch bark with anti-inflammatory and skin-barrier supporting properties; betulin has been used in traditional medicine and is well-tolerated in cosmetic formulations.

Betulin (CAS 473-98-3, PubChem score 85) is a pentacyclic triterpene found predominantly in birch bark (Betula species). It is not listed in EU Regulation 1223/2009 Annex II (banned) or Annex III (restricted), indicating no specific cosmetic restriction. Published research demonstrates anti-inflammatory, antioxidant, and wound-healing properties. It has been used in traditional European folk medicine for skin conditions. Safety data is robust with no evidence of genotoxicity or sensitisation at cosmetic concentrations.

Skin benefits

  • Anti-inflammatory
  • Skin barrier support
  • Wound healing properties
  • Antioxidant
  • Soothing skin care applications

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.