Skin Conditioning
BIOTINOYL PENTAPEPTIDE-73
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic pentapeptide tethered to biotin, marketed for hair/skin conditioning. Safety looks low-risk at ppm use; efficacy evidence is thin.
Biotinoyl pentapeptide-73 is a proprietary synthetic peptide consisting of a five-amino-acid sequence N-terminally conjugated to biotin (vitamin B7). It is marketed for hair-growth-adjacent and skin-conditioning claims. Defined synthetic peptides generally have low irritation and sensitization profiles at cosmetic ppm concentrations. No SCCS or CIR monograph specifically covers this peptide, and independent efficacy data is limited — most claims rest on supplier studies. Purity (residual solvents, conjugation by-products) depends on manufacturer. Immunogenicity is theoretically possible with any foreign peptide but has not been reported at cosmetic exposure. Defaults-down rubric applies.
Function
Skin benefits
- Biotin-conjugated synthetic peptide — claimed hair/skin conditioning
- Low concentration use (ppm levels)
- Low irritation potential for defined peptides
Known concerns
- Efficacy data is largely supplier-driven
- No SCCS/CIR monograph for this specific peptide
- Long-term safety and immunogenicity data thin
- Biotin-conjugate purity depends on supplier
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.