BIS(1,4-PHENYLENEDIAMINE)-BENZOQUINONE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A benztriazine-quinone type hair dye intermediate with potent sensitisation potential, subject to EU Annex III restrictions for oxidative hair dye use only with mandatory declaration and special labelling requirements.
This compound is a benzoquinone derivative of 1,4-phenylenediamine, functioning as an oxidative hair dye intermediate/chromophore. Benzoquinone and its derivatives are recognised contact sensitisers, and combined with the phenylenediamine structure, this ingredient carries significant allergy risk. EU Annex III (list of substances which cosmetic products must not contain except subject to the restrictions laid down) applies to oxidative hair dye intermediates, requiring: (1) use only in oxidative hair dye products, (2) maximum concentration limits, (3) special labelling for allergy-prone consumers, and (4) prohibition in moustache, eyebrow, and eyelash products. Professional use only is typically recommended.
Known concerns
- Benzoquinone - known skin sensitiser and irritant
- Aromatic amine structure - PPD-related sensitisation risk
- Used in hair dye intermediates - EU Annex III applies
- Strong dye component - can stain skin
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.