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Antimicrobial / chelator (restricted)

bis(8-hydroxyquinolinium) sulphate

CAS 134-31-6
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A quinoline-based antimicrobial chelator restricted under EU Cosmetics Annex III, with concentration limits and partial bans due to suspected reproductive toxicity and sensitization concerns.

Skin benefits

  • Has antimicrobial and antifungal properties historically exploited in topical preparations
  • Chelates metal ions, which can stabilize some formulations
  • Was previously used as a preservative or stabilizer in select products

Known concerns

  • 8-Hydroxyquinoline and its sulphate are restricted in EU cosmetics under Annex III
  • Classified as suspected reproductive toxicant (Repr. 2) under CLP
  • Skin sensitization concerns documented in literature
  • Use limited to specific hair products with strict concentration limits; banned in body cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.