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BIS-AMINOPROPYL DIGLYCOL

CAS 4246-51-9
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A diamine compound with two amine groups positioned to act as a reactive intermediate, often used in professional hair care formulations. The primary and secondary amine groups make it highly reactive and potentially sensitizing.

Bis-Aminopropyl Diglycol is a specialty diamine surfactant/conditioning agent where two aminopropyl groups are separated by a diglycol ether linkage. The ether bond provides flexibility and some water solubility, while the two primary amine groups give high reactivity. In hair care, it can function as a reducing agent (in hair dyes/bleaches) or as a conditioning intermediate. The amine functionality is a known sensitizer, and the diglycol ether component has raised some toxicological concerns in certain contexts. EU regulations on amines in cosmetic products apply.

Skin benefits

  • Used in oxidative hair dye formulations
  • May provide conditioning effects in professional hair treatments

Known concerns

  • Skin and respiratory sensitizer due to amine functionality
  • Potential for nitrosamine formation
  • EU regulated/restricted in certain cosmetic applications
  • May cause irritation on direct skin contact

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.