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Anti-hair-loss active

BIS-DIAMINOPYRIMIDINE OXIDE ZINC ACETATE

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A zinc-acetate complex of bis-diaminopyrimidine oxide aimed at slowing hair loss, with a mechanism close to minoxidil analogs. Evidence base is improving but long-term safety data remain limited.

Skin benefits

  • Targets the hair growth cycle similar to minoxidil analogs
  • May inhibit 5-alpha reductase locally
  • Combined with zinc, which itself supports scalp health
  • Used in leave-on anti-hair-loss products

Known concerns

  • Limited long-term human safety data for the bis-/zinc complex form
  • Earlier SCCNFP opinion on 2,4-diaminopyrimidine oxide flagged data gaps
  • Scalp irritation and dryness possible
  • Pharmaceutically active mechanism may not suit all users

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.