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Reactive crosslinker

BIS-(MALEIMIDOETHYLGLYCOLMETHYL) BICYCLOPENTANE

28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

This bismaleimide bicyclopentane is a highly reactive industrial crosslinker designed for polymer chemistry. Maleimide groups bind covalently to skin proteins, posing sensitization and toxicity risks unsuitable for cosmetics.

Skin benefits

  • Reactive bismaleimide crosslinker used in polymer chemistry
  • No demonstrated direct cosmetic benefit

Known concerns

  • Maleimide groups are highly reactive electrophiles binding to skin proteins
  • Bismaleimides are strong skin and respiratory sensitizers
  • No SCCS or CIR cosmetic safety review available
  • Industrial polymer chemistry origin not suited for topical use
  • Potential for irreversible covalent modification of skin biomolecules

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.