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BIS-(MALEIMIDOETHYLGLYCOLMETHYL) BICYCLOPENTANE

48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A complex bifunctional organic compound with maleimide groups — highly reactive groups that can form covalent bonds with proteins. Used in specialized biomedical and cosmetic material applications.

Bis-(Maleimidoethylglycolmethyl) Bicyclopentane is a sophisticated bifunctional molecule featuring two maleimide groups attached via an ethylene glycol linker to a bicyclic carbon skeleton. Maleimide groups are highly electrophilic and readily undergo Michael addition with thiol groups on proteins, making this class of compound useful for protein conjugation and crosslinking applications. In cosmetics, such compounds may appear in advanced peptide delivery or film-forming systems. The maleimide group is a known sensitizer, and the bicyclic core adds complexity. No CAS or specific EU regulatory data found.

Skin benefits

  • Potential for targeted peptide delivery systems
  • May be used in advanced film-forming cosmetic materials

Known concerns

  • Strong skin sensitization potential (maleimide groups)
  • High reactivity with skin proteins — potential allergen
  • Limited cosmetic-specific safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.