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BIS-METHOXYETHOXY METHANE

CAS 4431-83-8
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A glycol ether solvent historically used in cosmetic formulations for its excellent solvency and penetration-enhancing properties, now less common due to reformulation trends toward safer solvent systems.

Bis-methoxyethoxy methane (dimethylene glycol dimethyl ether) is a glycol ether solvent once used in cosmetic formulations, particularly nail polish removers and hair dye carriers. It has good solvency for a wide range of organic compounds and can enhance penetration of other ingredients through the skin. However, glycol ethers as a class have faced reformulation pressure due to reproductive and developmental toxicity concerns with some specific glycol ethers (such as 2-methoxyethanol and 2-ethoxyethanol, which are banned). This specific ether has a comparatively better safety profile, but regulatory scrutiny remains.

Known concerns

  • Ether solvent - potential for skin drying
  • May enhance penetration of other ingredients
  • Not commonly used in modern cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.