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BIS-PALMITOYL TROMETHAMINE

76

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lipid-like organic compound formed from palmitic acid and tromethamine ( Tris base), typically used in cosmetic formulations as a skin-conditioning agent or emulsifying component.

Bis-Palmitoyl Tromethamine is an organic compound resulting from the condensation of two palmitic acid molecules with tromethamine (2-amino-2-(hydroxymethyl)propane-1,3-diol). The structure is reminiscent of dialkyl amphoteric surfactants or ceramide-like molecules. Tromethamine is a widely-used pH adjuster in cosmetics that is generally well-tolerated. The bis-palmitoyl modification creates a lipophilic molecule suitable for skin-conditioning and emollient functions. No EU restrictions apply, and the compound is considered safe for use in rinse-off and leave-on cosmetic products.

Skin benefits

  • Skin-conditioning agent — improves skin feel
  • Emollient properties — softens skin
  • May support skin barrier function

Known concerns

  • Limited independent safety data specific to this compound
  • Palmitic acid component can clog pores in acne-prone skin (comedogenic)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.