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BIS-SH-PENTAPEPTIDE-38 PORPHYRA 334

85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic bifunctional peptide combining two identical pentapeptide sequences with Porphyra 334 (an algae-derived UV-absorbing compound), designed to protect skin from UV-induced photoaging.

Bis-sh-Pentapeptide-38 Porphyra 334 is an advanced cosmetic ingredient that conjugates two copies of a short pentapeptide sequence (sh-Pentapeptide-38) to Porphyra 334, an extract from the red alga Porphyra (nori). Porphyra 334 is a mycosporine-like amino acid (MAA) that functions as a natural UV-absorbing compound, providing broad-spectrum UV protection. The peptide component is designed to support collagen and extracellular matrix proteins. The bis-configuration doubles the functional groups, potentially increasing efficacy. Peptide and algae-based ingredients generally have excellent safety profiles.

Skin benefits

  • UV-protective benefits from Porphyra 334 (broad-spectrum UVA/UVB absorption)
  • Peptide component may support collagen and skin matrix
  • Anti-photoaging potential
  • Antioxidant properties from MAA compounds

Known concerns

  • Mild risk of peptide sensitization in very sensitive individuals
  • Algae extract could theoretically contain iodine

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.