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Conjugated peptide-MAA photoprotectant

BIS-SH-PENTAPEPTIDE-38 PORPHYRA 334

72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A pentapeptide linked to the algal mycosporine Porphyra-334, marketed for UVA-related photo-ageing support. Evidence rests on cell studies; independent cosmetic safety reviews are still limited.

Skin benefits

  • Combines a synthetic pentapeptide carrier with the mycosporine-like amino acid Porphyra-334
  • Porphyra-334 absorbs UVA with high molar extinction, offering photo-protective support
  • Antioxidant action reduces UV-induced ROS in keratinocyte studies
  • Helps limit MMP expression linked to photo-ageing

Known concerns

  • Very limited independent safety review on the conjugated peptide form
  • Stability in finished formulations requires careful pH and chelation control
  • Not a substitute for a registered UV filter and should not be marketed as sun protection

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.