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BISHYDROXYETHYL BISCETYL MALONAMIDE

CAS 149591-38-8
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A malonamide-based conditioning agent with dual hydroxyethyl and cetyl hydrophobic chains, this compound carries a Warning signal with H319 (eye irritation), H361f (suspected reproductive toxicity), and H413 (aquatic hazard) that reflect its structural complexity and potential for environmental persistence.

This bis-hydroxyethyl biscetyl malonamide is a dimeric fatty acid amide that functions as a skin and hair conditioning agent, providing substantive hydrophobic film formation. The cetyl (C16) chains deliver strong emollient character while the malonamide core introduces slight water affinity. The H361f (suspected reproductive toxicity) and H413 (aquatic hazard) classifications indicate regulatory concern about the substance's bioaccumulation potential and environmental persistence. EU Annex II/1243 indicates a specific restriction likely related to reproductive and aquatic hazard profile, limiting use to products where exposure is minimal.

Skin benefits

  • Strong emollient and skin conditioning properties
  • Forms substantive hydrophobic barrier on skin and hair

Known concerns

  • H361f suspected reproductive toxicity — environmental persistence concern
  • H413 aquatic hazard — not readily biodegradable
  • H319 eye irritation at elevated concentrations
  • EU Annex II/1243 restriction applies
  • High molecular weight may limit dermal penetration but raises accumulation concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.