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BROMOPHENYL PROPENAMINOETHYL ISOQUINOLINESULFONAMIDE HCL

CAS 127243-85-0/910228-02-3 (free base)
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A halogenated isoquinoline sulfonamide with multi-route exposure toxicity warnings requiring careful handling in cosmetic formulations.

This compound carries H302 (acute oral toxicity), H312 (dermal), H332 (inhalation), H315 (skin irritation), H319 (eye irritation), and H335 (respiratory irritation) classifications. The bromophenyl group combined with the sulfonamide and isoquinoline pharmacophore creates a reactive molecule. Under EU Regulation 1223/2009, ingredients triggering these hazard classifications require careful benefit-risk evaluation and may be subject to restrictions.

Skin benefits

  • Potential pharmacological activity of isoquinoline scaffold

Known concerns

  • H302/H312/H332: acute toxicity across multiple exposure routes
  • H315/H319/H335: irritation potential to skin, eyes, and respiratory tract

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.