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Preservative

Bronopol

CAS 52-51-7
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2-Bromo-2-nitropropane-1,3-diol — a formaldehyde-releasing preservative. EU caps it at 0.1% and prohibits combining with amines that could form nitrosamines; formaldehyde release drives the low score.

Skin benefits

  • Effective broad-spectrum preservative
  • Active at very low %
  • Useful in challenging formulations

Known concerns

  • Formaldehyde releaser
  • Can form nitrosamines with secondary amines
  • Skin sensitization and irritation
  • EU restricts use and bans in oral products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related preservatives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.