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BUTOXYETHYL ACETATE

CAS 112-07-2
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A glycol ether acetate (2-butoxyethyl acetate) used as a solvent in cosmetics; associated with blood effects (methemoglobinemia) at high exposure and requires handling precautions.

Butoxyethyl acetate (2-butoxyethyl acetate, CAS 112-07-2) is a glycol ether acetate used primarily as a solvent in cosmetic formulations, particularly nail polish and spray systems. PubChem safety score is 55. While not specifically listed in EU cosmetic annexes with prohibition, the compound has been associated with hematological effects (methemoglobin formation) at high exposure levels in occupational settings. Use in rinse-off products at low concentrations is considered safe, but leave-on and spray applications require caution.

Skin benefits

  • Solvent for cosmetic formulations

Known concerns

  • Methemoglobinemia concern at high occupational exposure
  • Respiratory irritant in spray applications
  • Eye and skin irritant

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.