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BUTYLPHTHALIDE

CAS 6066-49-5
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phthalide-type fragrance compound with a reported PubChem safety score of 55, showing mild irritation potential but no major acute toxicity at fragrance-use levels.

Butylphthalide (CAS 6066-49-5) is a benzenoid phthalide used as a fragrance ingredient. The PubChem safety score of 55 reflects moderate concern, primarily relating to insufficient toxicological data rather than strong evidence of hazard. It is not currently listed under EU cosmetic restrictions (Annexes II–VI) and is considered acceptable at typical fragrance-use concentrations.

Known concerns

  • Limited toxicological data available — precautionary concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.