Skip to content

Pharmaceutical-grade phthalide

BUTYLPHTHALIDE

CAS 6066-49-5
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A celery-derived compound mainly used as a prescription stroke medication in some countries. It causes skin, eye, and respiratory irritation and is not an established cosmetic ingredient.

Skin benefits

  • Bioactive compound found naturally in celery seed oil
  • Studied as a neuroprotective drug for ischemic stroke in some jurisdictions
  • Shows antioxidant and anti-inflammatory activity in laboratory studies
  • Some traditional culinary and herbal exposure history

Known concerns

  • GHS H315: causes skin irritation
  • GHS H319: causes serious eye irritation
  • GHS H335: may cause respiratory irritation
  • Primarily a pharmaceutical (NBP) used systemically, not a typical cosmetic ingredient
  • Crosses the blood-brain barrier easily, raising systemic exposure concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Check your shelf

Find BUTYLPHTHALIDE in your products.

Scan any cosmetic product with LuxSense to see if it contains BUTYLPHTHALIDE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.