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C16-alkyltrimethylammonium chloride C18-alkyltrimethyammonium chloride

CAS 112-02-7
43

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient. Exercise caution due to limited available safety data.

Cetrimonium chloride (CAS 112-02-7) and steartrimonium chloride are C16-C18 chain length quaternary ammonium compounds used as antistatic conditioning agents in hair care products. EU Regulation 1223/2009 Annex III establishes concentration limits of 2.5% for leave-on hair products and lower limits for other applications. The compounds carry hazard statements including H302 (harmful if swallowed), H312 (harmful in contact with skin), H314 (causes severe skin burns and eye damage), H317 (may cause allergic skin reaction), H400/H410 (aquatic toxicity), indicating significant safety concerns at higher concentrations.

Skin benefits

  • Provides antistatic conditioning in hair care products
  • Improves wet combing and reduces static
  • Softens hair texture and improves manageability

Known concerns

  • Concentration limits of 0.5-2.5% by product type in EU
  • Skin sensitizer (H317)
  • Eye and skin damage hazard (H314)
  • Aquatic toxicity (H400/H410)
  • Acute oral and dermal toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.