Skin Conditioning
CAPRYLOYLOXYPALMITOYL CAPRYLOYLOXYPALMITAMIDE MEA
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A pseudo-ceramide-style barrier-mimicking lipid with a monoethanolamine head group. Useful for dry-skin claims; modest nitrosamine caveat.
Caprylo yloxypalmitoyl capryloyloxypalmitamide MEA (CAS 1597432-40-0) is a synthetic pseudo-ceramide lipid combining caprylic and palmitic fatty acid chains with a monoethanolamide (MEA) head group. It is designed to mimic natural ceramide function in the stratum corneum and is used in barrier-support formulations. Compound-specific public toxicology data are limited. The MEA fragment is a secondary amide (not a free secondary amine), so direct nitrosamine formation is much less of a concern than with classic free-amine DEA/MEA compounds, but formulators should still avoid co-formulation with nitrosating agents (e.g., bronopol). No CMR or endocrine flags reported at use levels.
Function
Skin benefits
- Supports stratum corneum barrier
- Adds soft conditioning feel
- Synergistic with ceramide blends
Known concerns
- Avoid pairing with nitrosating preservatives
- Limited compound-specific data
- Newer molecule
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.