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Preservative

CETALKONIUM CHLORIDE

CAS 122-18-9 Updated
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A quaternary ammonium antimicrobial used at low levels in eye drops and rinse-off cosmetics. Considered safe at restricted concentrations, but the raw chemical is corrosive and aquatic-toxic.

Function

ANTIMICROBIALANTISTATICPRESERVATIVE

Skin benefits

  • Effective antimicrobial preservative
  • Used at low concentrations in eye drops and cosmetics
  • Cationic surfactant

Known concerns

  • GHS H314 — corrosive raw chemical
  • H302 harmful if swallowed
  • H400/H410 very toxic to aquatic life
  • Skin and eye irritant; restricted to low concentrations
  • Quaternary ammonium — possible sensitizer

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.