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CHINESE HAMSTER OVARY CELL/SH-POLYPEPTIDE-92 CONDITIONED MEDIA

35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Growth media conditioned by Chinese Hamster Ovary (CHO) cells engineered to express sh-Polypeptide-92, containing secreted proteins and cellular metabolites.

Chinese Hamster Ovary Cell/sh-Polypeptide-92 Conditioned Media is produced using CHO cells, which are classified as Category 1 material under Regulation (EC) No 1069/2009 when derived from controlled sources. Entry 419 of Annex II to EU Cosmetics Regulation 1223/2009 explicitly prohibits Category 1 and Category 2 animal materials in cosmetics. Regulatory review is essential before use; the conditioned media may also contain residual host cell proteins raising sensitization concerns.

Skin benefits

  • May deliver growth factors and secreted proteins for skin renewal
  • Potential anti-aging and skin-repair benefits from conditioned media

Known concerns

  • EU Annex II/419 restriction applies if derived from Category 1 animal material
  • Risk of residual host cell proteins causing sensitization
  • Requires documented origin and processing compliance

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.