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CHITOSAN HYDROXYPROPYLTRIMONIUM CHLORIDE

70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cationic polysaccharide derivative of chitosan with a hydroxypropyltrimethylammonium substituent, providing film-forming, moisture-binding, and antimicrobial properties.

Hydroxypropyltrimonium chloride is a water-soluble cationic derivative of chitosan (deacetylated chitin), modified with a 2-hydroxy-3-(trimethylammonio)propyl substituent. The substitution confers permanent cationic charge across a broad pH range, unlike basic chitosan which loses charge below pH ~6. Chitosan itself is listed in CosIng with no restrictions. The hydroxypropyl linker improves solubility and reduces the typical英国 of unmodified chitosan. Used in moisturizers, hair products, and wound-care formulations for its film-forming and antimicrobial properties.

Skin benefits

  • Strong moisture-binding (humectant) properties
  • Film-forming barrier on skin surface
  • Mild antimicrobial activity from cationic nature
  • Improves skin smoothness and softness

Known concerns

  • Possible residual chitin or protein impurities from chitosan source
  • Mild eye irritation at high concentrations
  • Skin drying if overused without adequate humectant combination

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.