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Chloro-N,N-dimethylformiminium chloride
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Chloro-N,N-dimethylformiminium chloride is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
This compound is the chlorinated iminium salt of N,N-dimethylformamide (DMF), formed by Vilsmeier-type activation. Its hazard profile overlaps significantly with DMF (H360D reproductive toxicity, H314 serious skin corrosion, H302 acute oral toxicity, H361 suspected reproductive toxicity). EU CosIng does not list this specific salt in Annex II or III, but the structural relationship to DMF and the Vilsmeier reagent's known toxicity place it in the severe concern range. It is primarily an industrial synthetic intermediate, not a functional cosmetic ingredient.
Known concerns
- H360D: May damage the unborn child — Category 1B reproductive toxicant
- H314: Causes severe skin burns and eye damage
- H302: Harmful if swallowed
- H361: Suspected reproductive toxicity
- Reactive iminium chemistry — high electrophilic reactivity with skin proteins
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.