Biotech active
CHOLECALCIFEROL/YEAST POLYPEPTIDE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Reaction product of vitamin D3 with yeast-derived polypeptides, used as a skin conditioning active. Limited regulatory review for cosmetic use of cholecalciferol conjugates means safety data is sparse.
Function
Skin benefits
- Yeast polypeptide fraction may support skin barrier
- Vitamin D3 moiety associated with skin homeostasis
- Conditioning effects in leave-on products
- Antioxidant peptide content
Known concerns
- Cholecalciferol is a vitamin with hormonal activity; topical exposure poorly characterized
- No specific SCCS opinion for this conjugate
- Yeast-derived fractions can vary in composition
- Potential allergenicity for sensitive users
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.