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Skin Conditioning

CHYMOTRYPSIN

CAS 9004-07-3
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A protein-cleaving enzyme from cow pancreas, used in skincare for gentle enzymatic exfoliation. Long medical track record, but its animal origin and rare protein-sensitization risk keep it in the cautious band.

Skin benefits

  • Enzymatic exfoliation of stratum corneum proteins
  • Anti-inflammatory in some clinical use
  • Gentler alternative to acid-based exfoliation

Known concerns

  • Animal-derived (bovine pancreas) — not vegan
  • Potential protein sensitization
  • Activity sensitive to pH and storage

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.